white-papers

White Papers

Title: geneO+ A Novel Skin Care Platform For Anti Aging And Rejuvenation Based On Unique OxyGeneo And TriPollar RF Technologies

Author: Alex Levenberg, M.D., Physicians Center, Plastic Surgery Dept., Tel Aviv, Uri Shpolansky, Ph.D. - Physiological Models

Date: October 2013

Abstract:
Aesthetic skin treatments are a common practice among women and men throughout the globe, crossing borders of culture and socio-economic status. Facials or skin treatments of various body areas have been popular throughout the ages and have been documented as early as ancient Egypt and Greece. A variety of treatments are available for exfoliation and infusion of skin enhancement products and there is a growing demand for skin oxygenation treatments. The innovative geneO+™ Skin Care Platform enables a variety of skin enhancement treatments for a wide range of skin characteristics. The OxyGeneo® treatment, provided by the geneO+ platform stimulates a unique sophisticated skin enhancement, utilizing the body’s natural mechanism for skin oxygenation from within. Skin oxygenation combined with light exfoliation and infusion of essential active ingredients, optimizes the effect of the treatment improving the overall feel and appearance of the skin. The geneO+ platform enables an add-on option of the well validated 3rd generation TriPollar radiofrequency (RF) technology for non-invasive dermal remodeling.

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Title: geneO+ A Novel Platform for Skin Revitalization Based on Unique OxyGeneo Technology

Author: Alex Levenberg, M.D., Physicians Center, Plastic Surgery Dept., Tel Aviv, Uri Shpolansky, Ph.D. - Physiological Models

Date: October 2013

Abstract:
Aesthetic skin treatments are a common practice among women and men throughout the globe, crossing borders of culture and socio-economic status. Facials and skin treatments on various body areas have been popular throughout the ages and documented as early as ancient Egypt and Greece. A variety of treatments are currently available for exfoliation and infusion of skin enhancement products and there is a growing demand for skin oxygenation treatments. The innovative geneO+ Skin Care Platform enables a variety of skin treatments for a wide range of skin characteristics. OxyGeneo treatment, provided by the geneO+ platform enables a unique sophisticated skin enhancement, utilizing the body’s natural mechanism for skin oxygenation from within. Skin oxygenation combined with light exfoliation and infusion of essential active ingredients, optimizes the effect of the treatment improving the overall feel and appearance of the skin.

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Title: Hybrid Energy Technology - A Novel Micro-Needles Technology for Skin Treatment

Author: Alex Levenberg, M.D., Physicians Center, Plastic Surgery Dept., Tel Aviv, Cruzira T Salazar, M.D, Pollogen Ltd. Clinical Dept., Tel Aviv, Israel, Marie Christine Branchet, PhD, Sylvie Boisnic, M.D, GREDECO Research Association, Paris, France.

Date: September 2012

Abstract:
Demand for skin rejuvenation and anti-aging procedures with minimal down time and low risk has led to the development of methods for non-surgical treatment of wrinkles, scars and general facial enhancement. In the past few years, fractional radiofrequency (RF) systems have been introduced that enable controlled skin resurfacing. The new Hybrid Energy™ (HE) micro needles technology delivers hot and electrical energies creating micro ablation thus promoting natural fractional healing process for dermal refilling and skin renewal. The objective of the current research was to evaluate the safety and effectiveness of the novel Surgen device HE applicator for collagen remodeling, skin volume refilling and wrinkles reduction.

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Title: TriFractional: A Novel Fractional Radiofrequency Technology for Skin Resurfacing and Treatment of Wrinkles clinical and Histological Results

Author: Alex Levenberg, M.D., Physicians Center, Plastic Surgery Dept., Tel Aviv, Israel Andrea Gat, M.D., Head of Dermatopathology Unit, Sourasky Medical Center, Tel Aviv, Israel

Date: September 2011

Abstract:
The need for cosmetic facial enhancement procedures with minimal down time and low risk has led to the development of methods for non-surgical skin rejuvenation. Various ablative lasers were developed, which remove the full skin surface in a controlled manner. However, the prolonged recovery and the significant risks prompted the development of fractional lasers which ablate the skin in a fractional manner, leaving untreated areas to improve healing process. In the past few years, fractional RF systems have been introduced that enable controlled skin resurfacing accompanied with dermal collagen remodeling. The new TriFractional technology from Pollogen is designed to enable skin resurfacing and treatment of wrinkles using radiofrequency energy. The objective of the current research was to evaluate the safety and effectiveness of the novel TriFractional technology using the TriFractional applicator (A3F) for micro-ablative skin resurfacing and the treatment of wrinkles.

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Title: TriLipo - A novel non-invasive technology for body shaping using the Maximus system.

Author: Alex Levenberg, M.D. Physicians Center, Plastic Surgery Dept., Tel Aviv, Israel
Date: March 2010

Abstract:
Aesthetic procedures aiming at non-invasive localized fat reduction, circumference reduction, cellulite improvement and skin tightening are desired worldwide to substitute surgical, invasive procedures. Non-invasive treatments using RF, laser, IR light, ultrasound or muscle toning procedures are common practice but do not provide the optimal solution in terms of efficacy and drainage of the internal released fat. The Maximus is a novel medical grade non invasive system that uses cutting edge TriLipo technology, for the purpose of body shaping by reducing and removing localized fat.
The TriLipo technology combines thermal RF effect for fat reduction and skin tightening with simultaneous active drainage. This triple action enables patients to benefit from visible immediate and long term results using a simple "walk-in, walkout" pleasant treatment.

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Title: Apollo - TriPollar Non-surgical facial treatment

Author: Alex Levenberg, M.D. Physicians Center, Plastic Surgery Dept., Tel Aviv, Israel

Date: June 2009

Abstract:

Objective: To evaluate the safety and efficacy of the apollo device for facial treatments.
Methods: Seven female subjects underwent facial treatments once a week using the apollo system. The system is equipped with both a medium and a small applicator specifically designed for facial treatments. Results were objectively recorded and analyzed with a three-dimensional imaging system.
Results: Following the apollo facial treatments, an improvement of perioral and periorbital wrinkles was achieved and analyzed using the Primos imaging system.
Conclusions: Findings demonstrated the safety and efficacy of the Apollo treatment protocol for facial skin tightening.Treatments resulted in tighter,‘lifted’ skin with improvement of fine lines and wrinkles.


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Title: Circumference reduction by TriPollar rf technology using the apollo device

Author: Alex Levenberg, M.D. Physicians Center, Plastic Surgery Dept., Tel Aviv, Israel

Date: September 2008


Abstract:
Background: Aesthetic procedures aiming at circumference reduction are desired by both women and men worldwide.Non-invasive treatments using IR light,RF,laser or ultrasound are common practice but do not necessarily provide the optimal solution. apollo is the first medical grade non invasive system that uses cutting edge 3rd generation TriPollar RF technology, for the purpose of circumference reduction.
Objective: The Evaluation of the safety and efficacy of the apollo device for non invasive treatment of excess fat manifested by circumference reduction. Method: 37 healthy female patients in three clinics underwent sessions of TriPollar treatments using the apollo.The treatment was performed in the body at a week interval between sessions. Results were assessed using photographs and circumferential measurements.
Results: Significant reduction in body circumferences was observed following the treatment period. The average circumferences reduction in main body areas (abdomen, buttocks, thighs), was 3.6 ± 2.4 cm with a maximum reduction of up to 10.5 cm in the abdomen. No adverse events were recorded during the evaluation period.
Conclusion: The apollo powered by TriPollar technology is a safe and effective procedure for the
treatment of excess

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Title: TriPollar RF Non-Surgical Face Lift & Skin Tightening - Long Term Results

Author: Omer Buhsem, M.D., D'estetica Aesthetic & Plastic Surgery, Bursa, Turkey

Date: February 2008

Abstract:
Background: It has been well established that TriPollar RF treatments depict immediate visible results. The question of long term collagen remodeling and maintaining the clinical results have been addressed in this study by way of thorough analysis.
Objective: This study aims to determine the long term clinical efficacy and safety of the non¬ablative Regen system, employing TriPollar RF technology, in the treatment of skin tightening and circumference reduction of facial, neck and abdominal skin.
Method Subjects enrolled in the study were healthy female patients between the ages of 18¬65 with lax and excess fatty facial, neck and abdominal skin were recruited for the study. Using the Regen system, the subjects (patients) underwent a regimen of 8 TriPollar RF treatments at weekly intervals. Throughout the study, before and after each treatment, the patient’s progress was photographically documented. Treatments continued until a full treatment course was concluded and expectations were met. These results were evaluated during a final clinical assessment 6 months after the last treatment, which included patient self-assessment as well.

Results: Immediate visible results were noticed from the first treatment. The patient’s results, observed gradually over the full course of treatment, revealed a significant circumference reduction and observable lifting of sagging skin. Further, these clinical results improved 6 months after last treatment due to collagen remodeling. The patient’s self¬assessment after the full course of the treatment was “excellent”. No adverse side effects during or after any of the treatments. Further, throughout the study none of the patients experienced any need for downtime following any of the treatments.
Conclusions: This clinical study concluded a very good overall improvement in skin laxity and circumference reduction with absolutely no downtime for any patients.The TriPollar RF treatments are safe and effective for non¬surgical face lifting, skin tightening and circumference reduction on all skin types. Long term results are excellent.

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Title: TriPollar RF Skin Tightening & Circumference Reduction Treatment on Asian Skin

Author: Sehyun Kim, M.D., Lyhn Clinic, Seoul, Korea

Date: November 2007

Abstract:
Background: It has been well established that Asian skin types are more sensitive to laser or IPL treatments (light¬based treatments) due to a larger concentration of melanin in the skin. A new non ablative treatment modality based on selective electro¬heating, TriPollar™ RF Technology, was recently introduced aimed at skin tightening for skin laxity and circumference reduction on facial, neck and arm skin. As this new treatment does not utilize any type of light it is not skin color dependent and is wholly suitable for Asian skin types.
Objective: This study aims to determine the clinical efficacy and safety of the non ablative Regen system, employing TriPollar RF technology, in the treatment of skin tightening and circumference reduction of facial, neck and arm skin in Asian skin types.
Method 100 Asian adult patients with lax and excess fatty facial, neck and arm skin were recruited for the study. Using the regen™ system, the patients underwent a regimen of one TriPollar RF treatment at weekly intervals. Throughout the study, before and after each treatment, the patient’s progress was photographically documented. Treatment continued until expectations were met. These results were evaluated during a final clinical assessment, which included patient self assessment as well.
Results: Immediate visible results were noticed from the first treatment. As seen in the photographs below (fig. 7), the patient’s results, observed gradually over the full course of treatment, revealed a significant circumference reduction and observable lifting of sagging skin. The patient’s self¬assessment after the full course of the treatment was “excellent”. This patient experienced no adverse side effects during or after any of the treatments. Further, throughout the study none of the patients experienced any need for downtime following the treatments.
Conclusions: This clinical study concluded a very good overall improvement in skin laxity and circumference reduction with absolutely no downtime for any patients. The TriPollar RF treatments are safe and effective for skin tightening and circumference reduction on Asian skin types. Further studies are needed to optimize the number and frequency of treatments.

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Title: A Novel Non-Invasive System For Skin Tightening And Cellulite Reduction Using The Innovative TriPolar™ RF Technology

Author: Alex Levenberg, M.D., Physicians Center, Plastic Surgery Dept., Tel Aviv, Israel

Date: Oct. 2006

Abstract:
Cellulite is one of the most disturbing and challenging skin disorders affecting the lives of more than 80% of women worldwide. Current treatments consist of: Liposuction, deep mechanical massage, applying pharmacological agents, exercise and diet regimens. Any of these treatments can reduce the signs of cellulite and its symptoms to some extent and only temporarily. It is now evident that weakened connective tissue, enlarged fat cells, and diminished micro-circulation, play key roles in the patho-physiology of cellulite. Therefore, long term correction of cellulite is possible through the modification of weakened connective tissue, reducing fat cell size and improve the overall function of micro-circulation.

Regen, from Pollogen Ltd., is an innovative system for the treatment of cellulite and skin tightening using TriPolar RF technology. The combined effect of uni-polar RF and bi-polar RF is a unique feature of this technology and provides simultaneous deep and shallow dermal heating/tightening. Treatment results include: reduction in size of fat cell size, enhancement of micro-circulation, enhancement of lymphatic drainage and controlled inflammation. The cosmetic effect is an immediate visible reduction of cellulite and skin tightening.

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